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We should emphasize that the results obtained here are site specific and need not generalize to other sites with different patient population profiles, non-primary care settings or structure of care provision. However, these results are similar to those obtained by other authors in real practice conditions. The coefficients of determination remained almost invariable after the addition of hospital diagnosis or correction of coding errors by the research team.

Only one patient with extremely high expenditure was excluded from the analysis. No other data were truncated to remove the effect of outliers.